A special protection agent (Ryan Reynolds) is tasked with guarding the life of his mortal enemy, who is one of the world's most notorious hitmen (Samuel L. Jackson), and taking him from England to the International Court of Justice.

On their way, they are on high-speed car chases and boat escapes as deadly assassins are pursuing them and they are forced to work together in order to defeat a ruthless, powerful and bloodthirsty Eastern European dictator (Gary Oldman).